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10 things you didn’t know about northwest science

admin — Fri, 21 Jul 2023 13:37:14 +0000

Science and technology in the Northwest led to many cutting-edge scientific discoveries, such as Britain’s first airplane, the birth of the first test tube baby, the splitting of the atom, and the world’s first computer. Science and technology continue to develop rapidly in this region, and many international brands, from medical research to military aircraft, have important research and design facilities in the northwest. More than 25% of the region’s £106 billion economy comes from science and technology companies.

1. North West universities play a major role in science and technology, and have a combined turnover of more than £1.2 billion, roughly 1% of the region’s total economy. Leading businesses, including those in the aerospace industry, automotive supply and manufacturing, nuclear energy and medical research, are closely associated with Northwestern universities. More than 50,000 students graduate from Northwestern each year, including 25,000 with life sciences degrees. More than 69,000 science students are trained each year.

2. North West Aerospace has sales of £6 billion and is responsible for the production of military and commercial aircraft and components that are used in the UK and exported around the world. Extensive research and development programs ensure that the latest technology is available to create the most advanced aircraft in the world. Countries around the world depend on the North West Aerospace Business for their military and commercial aircraft requirements

3. The chemistry industry plays a vital role in the North West and chemical sales contribute over £10 billion to the economy, which is approximately 20% of the UK chemistry industry. This sector employs approximately 220,000 people. In 2005, the Department of Trade and Industry announced that, as part of the Technology Program, it would be one of 19 new Knowledge Transfer Networks (KTNs) in Chemistry in the Northwest. KTNs help exchange knowledge and research between companies and academic institutions such as universities and trade associations.

4. The North West and Cumbria in particular, is widely recognized as the center of the UK’s nuclear power industry and is home to the Nuclear Decommissioning Authority. The research and development work carried out in this area has led the Government to conclude that the use of nuclear power is part of a viable solution to meet the UK’s energy needs.

5. There are more than 50 research institutes, many of which are multi-enterprise, in addition to the traditional research and development departments. The Northwest is home to the research and development divisions of many of the world’s leading companies, and investment in research and development for business in this region is greater than in any other part of the world except Asia. Recent reports show that 4 of the top 10 companies by R&D spending have significant facilities in the Northwest. Pharmaceutical development, including the UK’s largest center for cancer drug research, aviation and space companies, and consumer product manufacturers, as well as the chemistry and nuclear energy industries are well represented in the North West.

6. The seven science parks in the northwest are home to many knowledge-based companies in diverse industries ranging from education provision to nuclear power and decommissioning. Strong links with universities, research institutes and centers of knowledge, in the UK and abroad, help ensure that science and technology in the North West is second to none.

7. Dedicated strategic science and technology sites have been established across the North West, and Manchester aims to become one of the first six science cities in the UK by 2015.

Manchester Science Park is internationally recognized as a center of excellence, and is one of the most successful of its kind. Tenants include healthcare, communications and digital media professionals.

The Daresbury Science and Innovation Campus, near Warrington in Cheshire, is home to leading companies in diverse industries ranging from healthcare research to business support services. The nearby Daresbury Laboratory is one of the best resourced science facilities in the UK.

Liverpool Science Park, located right in the center of Liverpool, is the UK’s fastest growing science park, containing computer games, web design and software companies as well as lawyers specializing in intellectual property and technology law. Speke, also in Liverpool, is home to the National Biomanufacturing Centre, which is set to become Europe’s leading biopharmaceutical design centre, helping to create and develop new medicines.

West Cumbria Science Park, near Whitehaven, has more than 60 companies on site, ranging from environmental to engineering, many of which are involved in the nuclear power industry.

Lancaster’s Science Park is set to be developed this year, and will fall close to the top ten ranked universities. This exciting new project will combine academic knowledge with the resources of the renowned University, the knowledge of local business and the Lancaster Environment Centre.

8. With Manchester recently voted the most innovative city in the UK, and Liverpool’s reputation as one of the leading cities in computer game design, the North West is at the forefront of new technologies as well as traditional science and technology. The use of ICTs in education, website design, Internet technologies, television and film production, as well as other media industries, is booming in the region thanks to science and technology.

9. As well as looking to the future, the scientific history of the area is preserved through museums such as the World Museum in Liverpool, the Quarry Bank Mill in Styal, Cheshire and Wigan Pier. Visual displays as well as hands-on activities, demonstrations, and different media show how science and technology have changed our lives, from mechanizing everyday tasks to revolutionizing manufacturing methods.

10. In addition to its outstanding science and technology facilities, the Northwest is a popular business location thanks to its impressive infrastructure. Close to 3 international airports, and a great highway system, North West is closer than you think. In addition, in the northwest there are many areas of outstanding natural beauty and a high standard of living.

There has never been a better time than now to find out how North West Science and Technology can help you.

Implementing a Quality Management System for Pharmaceutical Products

admin — Fri, 21 Jul 2023 13:37:11 +0000

The pharmaceutical industry is one of the highly regulated manufacturing businesses. Quality management systems have a direct impact on the final quality of finished products. However, the quality of these products reflects not only the legislative requirements but the essence and competence of the pharmaceutical practitioner.

Due to the importance attached to the pharmaceutical industries, just like the food industries, they are used directly by the consumers for either local application or internal consumption. The quality, safety and efficacy attributes of these pharmaceutical products must be ensured, for this reason, so that the health of the consumer is not compromised. To ensure high quality and guaranteed safety, high quality pharmaceutical industries are required.

To achieve this, pharmaceutical companies must follow strict guidelines and regulations set by health authorities such as the FDA (Food and Drug Administration) in the United States or the EMA (European Medicines Agency) in Europe. These guidelines cover all aspects of production, from sourcing raw materials to packaging and distribution.

One key aspect of ensuring quality in pharmaceutical manufacturing is through a robust Quality Management System (QMS). This system includes various processes and procedures that are implemented to ensure consistent quality throughout the manufacturing process. QMS also helps in identifying and addressing any potential issues or risks before they can impact the final product.

In addition to regulatory requirements, pharmaceutical companies also follow international standards such as Good Manufacturing Practices (GMP) and International Organization for Standardization (ISO). These standards ensure that the manufacturing process is in line with best practices and meet high-quality standards.

Moreover, pharmaceutical companies also invest heavily in research and development to constantly improve and innovate their products. This includes conducting clinical trials to prove the safety and efficacy of new medications before they are released to the market.

Pharmaceutical industries are committed to complying with global life sciences quality standards while involved in either the production, supply or consumption of pharmaceutical products. There are globally recognized bodies that regulate the quality of pharmaceutical substances and their products.

Having a good understanding as well as implementing an appropriate quality management system is a prerequisite for every type of trader in this pharmaceutical sector to fulfill the regulatory as well as ethical responsibility to integrate the management of the identity, safety, purity, quality and potency of finished medicinal products.

For most biotech and pharmaceutical companies, managing training, business processes, and documentation are their nightmares. In this article, we will explore quality management systems and how one should explore them and manage the processes successfully.

Quality Management Systems in the Pharmaceutical Industry

A quality management system (QMS) is a set of processes, procedures, and policies that govern the quality control and assurance efforts within an organization. In the pharmaceutical industry, QMS plays a critical role in ensuring that products are manufactured to meet regulatory standards and deliver safe and effective medications to consumers.

There are several key components of a QMS that are relevant to the pharmaceutical industry, such as:

Training and competency management: This involves ensuring that employees are trained and competent in their roles to perform their tasks effectively. This is crucial in the pharmaceutical industry, where accuracy and attention to detail are paramount.
Document control: In this highly regulated industry, proper documentation is essential for compliance and traceability. A QMS helps to organize and manage documents, control revisions, and ensure that the correct version is being used.
Corrective and preventative actions (CAPA): When issues or discrepancies arise in the manufacturing process, a QMS can help track and address these through CAPA procedures. This involves identifying the root cause of the issue, implementing corrective actions, and preventing the problem from recurring in the future. This is vital for maintaining product quality and compliance.
Change control: In a constantly evolving industry, changes are inevitable. A QMS can help manage and document changes to processes, equipment, or materials to ensure that they do not affect product quality or regulatory compliance.
Auditing and inspection management: External audits and inspections are common in

Request

The quality manufacturing system component of pharmaceutical products can be applied in pharmaceutical development to:

• Formulation development (container/closure system)

• Manufacturing research products.

Drug development

• Developing the analytical method

• Develop a delivery system (when needed)

• Expanding and developing the manufacturing process

Beneficiaries of pharmaceutical quality systems

R&D document authors: In addition, effective quality management systems easily export author documents from compatible templates. Authors don’t need to worry about reformulating documents to fit templates. Word 2007 users can create, revise, and even red outline documents without having to leave Word while using the new systems toolbar. R&D managers (clinical, regulatory and pre-clinical): They can use different types of pharmaceutical quality management software systems such as master control, to search, organize and inventory various study documents within the secure and centralized quality management system. With the automated routing and approval functionality of Quality Systems, managers can easily supervise project teams made up of resources from different departments, inasmuch as the teams may be working on different projects at the same time. Advanced pharmaceutical quality management systems also enhance communications from various regulatory agencies, suppliers and CROs, associated with appropriate documentation. With effective quality management systems, PDFs containing content cross references can be automatically generated for either document control functions or organizational submissions. As most pharmaceutical quality management software are complete, connected systems, authors do not need to constantly navigate through various different systems (from word to email and then to a document management system, etc.) to locate or review a document, and then submit it for review or approval – quality management systems such as master control allow such actions to be taken within one integrated system.

Administration: In the part of life sciences organizations, pharmaceutical quality systems are known for providing comprehensive solutions that ignore existing internal capabilities. Should the organization need training on system functionality or need assistance configuring the system to suit specific needs, Pharmaceutical Guayaquil, Ecuador It can be modeled with any level of service required, or support that the organization needs. An organization that needs expert knowledge can have a skilled quality management consulting team analyze the conditions in order to clearly define and develop these requirements.

Manufacturing processes: These systems easily track all specifications, non-conformities and deviations throughout the development cycle. Pharmaceutical management systems provide that all appropriate personnel receive training in the latest work instructions and standard operating procedures. Likewise, these systems automate training tasks and make it easy to locate training records within the central system.

Clinical staff: Within clinical circles, pharmaceutical quality management systems rid management of backlogs of paper files that lead to “black holes” of documents that are nearly impossible to find. Now that quality management systems are electronic and automated, searching the archives for experimental documentation (IRB information or protocols) is simple. Resumes, electronic document copies, e-mails, etc., from various study sites, are easily accessible in one centralized system. This allows clinical staff to focus on their core responsibilities and ensures that all necessary documentation is readily available for regulatory reviews.

Regulatory compliance: Pharmaceutical quality systems provide an organized and efficient approach to maintaining regulatory compliance. With features such as automatic audit trails, real-time monitoring, and customizable reporting, these systems ensure that all processes are in line with regulations and standards set by governing bodies. This not only helps companies avoid citations and penalties, but also promotes transparency and accountability in the industry.

Supply chain management: The use of pharmaceutical quality systems has greatly improved supply chain management. These systems allow for real-time tracking of materials, ingredients, and finished products from suppliers to production facilities to distribution centers. With this level of visibility, any issues or delays can be quickly identified and addressed, minimizing the risk of product shortages or recalls. Furthermore, pharmaceutical quality systems aid in maintaining accurate inventory levels and expiration dates, reducing waste and ensuring that products are delivered to customers on time.

Overall efficiency: The overall efficiency of a company is greatly enhanced by implementing pharmaceutical quality systems. These systems eliminate manual processes, reduce paper usage, improve communication among departments, and provide real-time data for better decision making. This results in streamlined operations, cost savings, and improved productivity.

Continuous improvement: Pharmaceutical quality systems promote a culture of continuous improvement within an organization. By analyzing data and identifying areas for improvement, companies can implement corrective actions that lead to enhanced processes and products. These systems also allow for the tracking of key performance indicators (KPIs) to monitor progress and ensure that quality standards are consistently met.

Customer satisfaction: Ultimately, pharmaceutical quality systems help to ensure customer satisfaction. With a focus on quality and continuous improvement, companies can deliver products that meet or exceed customer expectations. This not only leads to increased customer loyalty but also helps to maintain a positive reputation in the market.

In conclusion, the implementation of pharmaceutical quality systems is crucial for the success of any company in the pharmaceutical industry. These systems provide numerous benefits, including compliance with regulations, improved visibility and efficiency, continuous improvement, and customer satisfaction. As technology continues to advance, it is important for companies to stay current with their quality systems in order to remain competitive and maintain high standards in the production of safe and effective pharmaceutical products. By prioritizing quality, companies can build trust with customers and ensure the health and well-being of patients who rely on their medications. So, it is important for companies to continuously review and improve their quality systems in order to stay ahead in the highly regulated pharmaceutical industry.

Future trends: As technology continues to advance, so do opportunities for further improvement and innovation in pharmaceutical quality systems. In the future, we can expect to see more use of automated systems such as artificial intelligence (AI) and machine learning to further enhance efficiency and accuracy in quality control processes. Additionally, the rise of digitalization and data analytics will provide companies with even more insights into their processes, allowing for quicker identification of issues and opportunities for improvement.

Quality management system in medicines

admin — Fri, 21 Jul 2023 13:37:10 +0000

to request

The quality manufacturing system component of pharmaceutical products can be applied in pharmaceutical development to:

• Formulation development (container/closure system)

• Manufacturing research products.

Drug development

• Developing the analytical method

• Develop a delivery system (when needed)

• Expanding and developing the manufacturing process

Beneficiaries of pharmaceutical quality systems

administration: In the part of life sciences organizations, pharmaceutical quality systems are known for providing comprehensive solutions that ignore existing internal capabilities. Should the organization need training on system functionality or need assistance configuring the system to suit specific needs, Pharmaceutical Guayaquil, Ecuador It can be modeled with any level of service required, or support that the organization needs. An organization that needs expert knowledge can have a skilled quality management consulting team analyze the conditions in order to clearly define and develop these requirements.

Facial transplants in the news

admin — Fri, 21 Jul 2023 13:37:09 +0000

Closer to science fiction than scientific fact, several people have undergone facial transplants in the past two years. Relegated to only the most egregious incidents, like most medical miracles, the techniques were perfected. Once that happens, it is only a matter of time until the procedure becomes available as an elective surgery for those who are not satisfied with their current face, or who may just want a new look. After all, who wants to walk around their whole life with the same old face? Wouldn’t it be nice to re-encounter your 25th high school reunion? Then again at thirty?

Fortunately, great strides have also been made in face transplants for your (and other) kitchen cabinets. Thanks to the mastery of materials and techniques, your kitchen can now be renovated on an optional and economical basis and, when done correctly, is indistinguishable from a new kitchen, beautifying all those unsightly stains that have embarrassed you for years.

In the not too distant past, a few brave practitioners risked their reputations by using early crafting techniques. You can choose from a catalog of about three different renovation styles and colors, most of which were flimsy laminate doors with no detail. To make matters worse, the material was cemented to the face of the tanks using contact cement, which is a highly toxic and flammable adhesive with a life expectancy of 10 to 15 years. Not very tempting!

So scientists at Minnesota Mining & Manufacturing (3M) got down to business and created a new adhesive that is non-toxic, non-flammable, odorless, and only gets stronger with age! It doesn’t get any better! Then someone (I’m not sure exactly who) developed a material called Rigid-Thermofoil, also known as RTF. This fantastic new product is a vinyl-like material that is incorporated into a furniture grade composition board. Using computer-controlled heat and pressure to create the final product, it’s flexible and much more resilient than the old slats of yesteryear, and it can be molded into doors of various shapes enabling manufacturers to create hundreds of exciting patterns. But they didn’t stop there. New imaging techniques have been developed to replicate the beauty of real wood. This year, they even introduced an RTF product that looks just like stainless steel, creating a very modern and attractive look for your cabinets.

In 1951, famous industrial designer Raymond Lowe (and one of my personal heroes) wrote a book called Don’t leave enough alone. Apparently, manufacturers who make wood doors for refurbishment discovered this book recently because they decided to introduce alternative doors with new wood shapes and types. It’s no longer relegated to just oak, maple, and cherry. Now you can freshen it up with eco-friendly bamboo, walnut, mahogany, and sapele to name a few. Then the guys at 3M got together with the fabricators who made wood veneers and it was a marriage made in heaven.

So, if an unforeseen disaster has deteriorated all of your closet, now is the time to investigate a renovation. As the procedure has become more popular, the cost associated with the operation has dropped dramatically, just as people who return for treatment after it will also become more routine.

Modern science has taken giant steps forward in reforming people as well as kitchens. To quote the Wicked Witch of the West, her face plummeted, “What a world, what a world!” (Unfortunately, her face and the rest of her face had melted to the point where a transplant would not be recommended.) But she would have had a nice kitchen.

Science, technology, information technology and space

admin — Fri, 21 Jul 2023 13:37:08 +0000

The title of the fastest in the world was awarded to the American computer
According to reports on November 15, 2012, the Cray supercomputer at the US government’s Oak Ridge National Laboratory was an IBM supercomputer at another US research center. The Titan, Oak Ridge’s proven Cray XK7 system, achieved 17.59 peta flops (quadrillion calculations per second). The system is funded by the US Department of Energy, and is used for research on energy, climate change, engines, active materials, and other advanced scientific research.

The titan IBM Sequoia at Lawrence Lever National Laboratory, California, has beaten to second place. Sequoia, which was declared the world’s fastest system in June 2012, can only manage 16.32 beta flops in the competition. In the top five, the others were a Fujitsu K computer in Kobe, Japan; Mira IBM Blue Gene / Q system in Chicago, USA; And another IBM Blue Gene/Q system named Queen in Germany. The survey found that 251 of the world’s 500 fastest systems were in the USA, 105 in Europe and 123 in Asia, including 72 in China.

Scientists discover how to change the color of gold
Scientists have discovered for the first time a way to change the color of gold, the world’s most famous precious metal. Researchers from the University of Southampton, USA, have discovered that by etching small raised or overlapping patterns into the surface of a mineral, they can change the way it absorbs and reflects light. The result is that the human eye does not see it as “golden” at all.

This breakthrough discovery is applicable to other metals such as aluminum and silver. It opens up prospects for coloring minerals without the need to coat or chemically treat them, providing valuable economic, environmental and other benefits.

This technology can be harnessed in a wide range of industries that include jewelry manufacturing. It can also be used to make banknotes and documents that are difficult to counterfeit. It can be used to produce a wide range of colors on a particular mineral.

The glove that allows the hands to function as a wireless keyboard
Researchers from the University of Alabama, USA, have designed a new glove that allows users to transform into a wireless keyboard. Instead of tapping keys on a keyboard, the user simply touches their thumb to specific points on their fingers that are assigned a letter or other keyboard functions. The conductive thread carries the command to a matchbox-sized printed circuit board (PCB) affixed to the back of the glove. The PCB transmits it to the target device via Bluetooth.

The gauntlet’s name is Gauntlet, which is short for a low-power, publicly accessible electronic stamp. It features a honeycomb of conductive threads that run through the fingers and palm.

3D Scanning – Applying Science to Ghost Hunting

admin — Fri, 21 Jul 2023 13:36:56 +0000

3D laser scanners are well known for their use in the engineering and manufacturing industries, but in the entertainment industry? Not much. After its introduction in 1998, companies whose tasks could obviously be simplified by scanners, such as product design and manufacturing, immediately implemented laser scanning. However, in the past 12 years, laser scanning has reached an increasingly wide range of industries and organizations that can also take advantage of 3D scanning’s ability to gather precise physical data of objects, spaces, and environments—a recent example of which can be seen in the National Geographic Channel’s use of laser scanning to scan the interior of East Philadelphia State Prison—famous for being one of the most terrifying prisons in America.

According to National Geographic, since the prison’s official closure in 1971, caretakers and visitors to the prison have heard “eerie voices, screams and agonized screams, while others have seen shadows cast in and out of the cells.” Previously featured on various shows about the most haunted places in America, the prison was well known for its hair-raising tails before the National Geographic Channel took its turn. But the prison has not been thoroughly examined with hard science tools as well as suggestive tools commonly used by parapsychologists and psychiatric investigators, such as EVP and video recorders. As a result, viewers were able to travel inside the prison thanks to 3D animation generated from triangulation scans and see where ominous noises and strange sightings are supposed to occur, as evidenced by motion sensors, night vision, and infrared cameras.

The subject of the prison’s primary survey was the twelfth cell block, where more ghostly phenomena are said to occur than other cell blocks. For National Geographic scientists, the challenge was determining whether the cells did indeed display unexplained events or that such events were the result of those who believed in ghosts and therefore inadvertently understood the phenomena due to the prison’s ghostly reputation. To get an answer, the researchers decided to use laser scanning in combination with the aforementioned technology to identify any event in cell block 12. In terms of 3D scanning, triangulation scanners were chosen for their ability to scan relatively large areas with incredible accuracy.

In the end, as with the other famous hauntings, the ghostly goings-on of Eastern State Penitentiary cannot be legitimized or explained. But the presence of laser scanning, among other technologies, gave viewers a greater level of insight toward drawing their own conclusions. In addition to its use in documentary specials, laser scanning is also commonly used in the entertainment industry to create video game characters whose movements are based on real human movements.